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Cancer of the gallbladder can causes attacks of biliary pain, yellowing of the skin (jaundice), and weight loss.

A large gallbladder may be able to felt in the abdomen.

The gallbladder is divided into three sections: the fundus, body, and neck.

A full blood count may reveal an increased white cell count suggestive of inflammation or infection.The muscle fibres here contract to expel bile from the gallbladder. At any one time, 30 to 60 millilitres (1.0 to 2.0 US fl oz) of bile is stored within the gallbladder.Rarely, two or even three gallbladders may coexist, either as separate bladders draining into the cystic duct, or sharing a common branch that drains into the cystic duct. When food containing fat enters the digestive tract, it stimulates the secretion of cholecystokinin (CCK) from I cells of the duodenum and jejunum.It receives and stores bile, produced by the liver, via the common hepatic duct, and releases it via the common bile duct into the duodenum, where the bile helps in the digestion of fats.The gallbladder can be affected by gallstones, formed by material that cannot be dissolved – usually cholesterol or bilirubin, a product of haemoglobin breakdown.

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