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Audrey Payance Oregon Health and Science University482 Analyses of progressive disease patients with advanced hepatocellular carcinoma treated with sorafenib: prognosis, treatment, and progression pattern Keiko Yamane, Takahide Nakazawa, Wasaburo Koizumi Kitasato University School of Medicine483 Impact of Viral Hepatitis Etiology on Survival Outcomes in Patients with Hepatocellular Carcinoma: A Large Multicentre Study Sara Mgaieth Soonchunhyang University College of Medicine Seoul Hospita485 Survival and prognostic factors in patients with intermediate stage hepatocellular carcinoma (HCC) who were treated with repeated transarterial chemoembolization (TACE) Jung Hee Kim VA West Los Angeles Healthcare Center489 Albi score predicts survival in patients with BCLC 0/A stage Hepatocellular Carcinoma (HCC) independently of Child Pugh (CP) score and treatment allocation Simona Onali Department of Molecular and Clinical Cancer Medicine, University of Liverpool490 Albi score predicts survival independently of hepatic venous pressure gradient (HVPG) and indocyanine green (ICG) clearance in HCC patients undergoing resection Aileen Marshall Department of Molecular and Clinical Cancer Medicine, University of Liverpool491 Outcomes of patients with recurred intrahepatic cholangiocarcinoma after resection Hyeongmin Park National Cancer Center of Korea 492 Disruption of the HNF1a binding site abolishes UGT1A1 promoter activity: A novel pathomechanism of Crigler-Najjar syndrome Remco van Dijk Stanford University498 Methylation-associated silencing of Micro RNA-200b contributes human hepatocellular carcinoma progression by directly targeting Bmi1 Wen-rui Wu, Xiang-de Shi, Rui Zhang, Mansheng Zhu, Xian-huan Yu, Hong Zeng, Chao Liu, Lei-bo Xu Sun Yat-sen Memorial Hospital, Sun Yat-sen University499 Molecular mechanisms underlying the unprecedented liver regeneration induced by ALPPS surgery. Singal Research Institute for Radiation Biology and Medicine, Hiroshima University552 Suboptimal Quality Of Preventive Liver Care Among IBD Patients On Long-term Steroid And Biologics: A Single Center Experience Chuan L. Te, Nancy Reau University of Chicago Hospitals554 Abdominal Ultrasonography Guidance Strongly Reduces The Risk Of Complications And Improves Success Rate After Liver Biopsy: Results Of A Meta-Analysis Comparing The Use Of Ultrasound Guidance To The "Blind Method" Armand Garioud Vichaiyut hospital and Medical Center556 Living Liver Donors: Disparity, Distress, and Sleep Michelle T.Magda Langiewicz, Andrea Schlegel, Bostjan Humar, Rolf Graf, Pierre A. Miao, Sara West, Korta Yuasa, Michael Komar, Robert E. Jesse, Reema Habra, Steven Mekaru, Eric Goldstein, Anne Eshelman, Marwan S.Clavien University Hospital Zurich500 Identifying novel therapeutic targets in HCC through an integrated transcriptomics and pharmacogenomics approach Bin Chen Stanford University501 Defective m TOR-TFEB signaling in Human Hepatocellular Carcinoma Rajesh Panigrahi, Partha K. Jensen, Nancy Reau The University of Chicago540 Hepatitis B Testing Prior to Administration of Rituximab, Ofatumumab and Obinutuzumab in the National Veterans Affairs Health Healthcare System, 2002-2014. Hunt Central Arkansas Veterans Heathcare System541 Comparable hepatitis C treatment outcomes with oral direct-acting antivirals between rural outreach clinics and an academic medical center: A case for expanding task-shifting Channa R. Perumpail, Aijaz Ahmed Stanford University Medical Center542 Reducing Wait Times for Radiofrequency Ablation in Patients with Hepatocellular Carcinoma: A Quality Improvement Initiative at the Toronto Centre for Liver Disease. Smith, Stacy Prall Geisinger553 Disparities in the Quality of Death and Resource Utilization in End-Stage Liver Disease John N. Abouljoud Henry Ford Health System557 Palliative Care Services are Underutilized in Liver Transplant Candidates Priya Kathpalia Bloomberg School of Public Health561 Rates of liver fibrosis assessment and treatment initiation with IFN-free regimens within a screening program for advanced liver fibrosis among HIV/HCV-coinfected patients Mattias Mandorfer Public Health England565 Distance to Transplant Center and Waiting List Outcomes Jordan Voss, Adam Mc Cann, Sean C.Chandra, Pauline Ferraris, Fatma Aboulnasr, Srinivas Chava, Tong Wu, Srikanta Dash TULANE MEDICAL SCHOOL502 Chimeric hepatitis E virus-like particles as a tool of oral vaccination against hepatitis A virus Eun Byul Lee Yonsei University College of Medicine505 A proof of concept nonclinical study: vorinostat-induced hepatocellular expression of MICA augmented anti-HCC effects of NK cells through NKG2D signaling Kaku Goto ISIS Pharmaceuticals, Inc.508 Shifting gut microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration Hui-Xin Liu, Ying Hu, Lili Sheng, Yu-Jui Yvonne Wan UC DAVIS509 Pre-operative plasma glypican-3 levels detected by a novel ELISA system predict the risk of post-operative recurrence in patients with stage I hepatocellular carcinoma Kazuya Ofuji Hyogo College of Medicine514 YAP Promotes Cyclin D1 Expression in Cholangiocytes and Hepatocytes Quy P. Mayur Brahmania University of New South Wales544 Learning the Liver: The Pilot Implementation of Hepatology-Focused Educational Interventions in Internal Medicine Residency Training Adam E. Kumer, Timothy Schmitt, Richard Gilroy Kansas University Medical Center566 Deleterious effects of cirrhosis on outcomes after firearm injury Sentia Iriana Arusha Lutheran Medical Centre573 Hepatitis C Virus Sustained Virologic Response Rates among Patients Treated in Primary Care Settings in New York State Colleen Flanigan, Jason Pendergast New York State Department of Health574 External Validity of Trials in Non-Alcoholic Fatty Liver Disease: Systematic Review of Randomised Controlled Trials and Non-Randomised studies Richard Parker Inova Health System576 Primary Care Physician Perspectives on Hepatitis C Virus (HCV) Screening, Diagnosis, Referral and Treatment in the Era of Highly Effective Oral Anti-Viral Therapy Mary Thomson, Monica Konerman, Anna S.Jin Kaohsiung Medical University Hospital, Kaohsiung Medical University368 Effect of Antiviral Therapy and REACH-B Risk Score on Hepatocellular Carcinoma (HCC) Incidence in Chronic Hepatitis B (CHB) Patients Who Did Not Meet Treatment Criteria by AASLD, US Panel, EASL, or APASL Guideline Nghia H. Costentin Beaujon Hospital374 Surveillance at six month intervals with ultrasonography performs good for the detection of early hepatocellular carcinoma in chronic HBV infection: a regular integrated 10 years follow-up experience Xiaoning Wu, Xiaoming Wang, Yameng Sun, Yuanyuan Kong, Yu Wang, Xinyan Zhao, Qianyi Wang, Weijia Duan, Hong You, Jidong Jia, Xiaojuan Ou Beijing Friendship Hospital375 Integrator complex subunit 6 (INTS6) is a prognostic marker for hepatocellular carcinoma Minqiang Lu Graduate School of Cancer Science and Policy, National Cancer Center, Korea378 Undetected asymptomatic alcoholic cirrhosis underlies the diagnosis of hepatocellular carcinoma (HCC) out of surveillance programs in Spain. Yoo, Ji Hoon Kim, Seong Hee Kang, Young-Sun Lee, Tae Suk Kim, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun Korea University College of Medicine406 Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features Fukiko Kawai-Kitahata University of Yamanashi407 Treatment not needed for hypovascular tumors associated with hepatocellular carcinoma Yutaka Midorikawa, Tadatoshi Takayama Nihon Univ.408 Elevated Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein predict all-cause mortality in hepatitis C patients with hepatocellular carcinoma Shigemune Bekki, Kazumi Yamasaki, Yuuki Sonoda, Yuki Kugiyama, Satoru Hashimoto, Akira Saeki, Shinya Nagaoka, Seigo Abiru, Atsumasa Komori, Hiroshi Yatsuhashi National Organization Hospital Nagasaki Medical Center409 Hong Kong Liver Cancer staging system is associated with better prognostic and therapeutic performance for hepatocellular carcinoma: Special emphasis on viral etiology Po-Hong Liu National Yang-Ming University410 Significant Suppression of Local Tumor Recurrence in Treatment for Hepatocellular Carcinoma with Peritumoral Vessels by Radiofrequency Ablation with Percutaneous Ethanol Injection: Propensity Score Matching Analysis Kazuhide Takata Meotoiwa Hospital411 Comparison of balloon-occluded Transarterial chemoembolization (TACE) with conventional TACE for treatment of hepatocellular carcinoma Takuro Niinomi, Masatoshi Ishigami, Yoji Ishizu, Teiji Kuzuya, Takashi Honda, Kazuhiko Hayashi, Yoshiki Hirooka, Hidemi Goto Nagoya Univercity Graduate School of Medicine412 Hepatic Decompensation After Transarterial Chemoembolization For Hepatocellular Carcinoma Dempsey Hughes, Fredric D. Stuart, FW Nugent, Sebastian Flake, Mary Ann Simpson, Amir A.

Mc Gill, Hartmut Jaeschke , Wen-Xing Ding The University of Kansas Medical Center599 Mitochondrial-shaping proteins as specific biomarkers to distinguish alcohol from fat-induced liver toxicity. Brain Newcastle University612 Vitamin A deficiency promotes hepatic expansion of resident (Kupffer cells) and peripheral (Gr) macrophages leading to excessive liver damage in rats with obstructive cholestasis. Hoeke, Janette Heegsma, Han Moshage, Klaas Nico Faber University Medical Center Groningen, Groningen, University of Groningen, The Netherlands613 The Modulation of Co-stimulatory Molecules by Circulating Exosomes in Primary Biliary Cirrhosis Takashi Tomiyama Nagoya City University Graduate School of Medical Sciences614 Increased expression of ORM1-like protein 3 (ORMDL3) in biliary epithelial cells may be related to the pathogenesis of primary biliary cirrhosis Motoko Sasaki Shizuoka Cancer Center615 Gene expression profiling of osteoblastic cells cultured with lithocholic acid or bilirubin.

Te University of Chicago272 Ascites Neutrophil Gelatinase-Associated Lipocalin (NGAL) Identifies Spontaneous Bacterial Peritonitis and Predicts Mortality in Hospitalized Patients with Cirrhosis Elizabeth C. Boyer Mallinckrodt Pharmaceuticals279 Efficacy and safety of intravenous norepinephrine (NE) plus albumin in the treatment of type 1 hepatorenal syndrome (HRS). Masato Nakai, Jun Itoh, Fumiyuki Sato, Seiji Tsunematsu, Takuya Sho, Goki Suda, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto Hokkaido University Graduate School of Medicine288 Acute kidney injury in cirrhotic patients undergoing contrast-enhanced computed tomography Roberto Filomia Unit Of Nephrology289 Acute kidney injury and short-term mortality after single 5 liter paracentesis without albumin infusion in cirrhotic patients with diuretic-resistant ascites Rodrigo Luz, Juliana R. Marta Tonon Bloomberg School of Public Health295 CA-125 significance in cirrhosis and its correlation with disease severity Raja G. Okoronkwo, Nikolaos Pyrsopoulos Rutgers New Jersey Medical School296 Predictive factors for a good response of tolvaptan for treatment of refractory ascites in cirrhotic patients Seiji Kawazoe Wayne State University School of Medicine308 Tacrolimus or Mycophenylate mofetil as a second-line therapeutic options in patients with Autoimmune Hepatitis: An international multicentre observational study. Mayne, Herbert Swanson Intercept Pharmaceuticals314 Longitudinal alteration in health-related quality of life and its impact on clinical course in patients with advanced hepatocellular carcinoma who received sorafenib treatment Masako Shomura University of Nagasaki315 Interferon (IFN), Ribavirin (RBV), Duration of Treatment and Baseline Patient-Reported Outcomes (PROs) Predict Adherence to the New Regimens for Treatment of Chronic Hepatitis C (CH-C) Zobair M.

Perez Federal University of Rio de Janeiro274 Slow, continuous low-dose albumin and furosemide infusion (SCLAFI) mobilizes large ascites safely in decompensated liver cirrhosis Gaurav Pande Sanjay gandhi post graduate institute of medical sciences275 Acute Kidney Injury in critically ill patients with chronic liver disease defined by the full KDIGO criteria: Incidence and Outcomes Roland Amathieu, Florentina E. Kellum University of Pittsburgh School of Medicine276 Low ascites levels of cell membrane-derived microparticles indicate worse short-term prognosis in patients with decompensated cirrhosis Cornelius Engelmann Charité - Universitätsmedizin Berlin277 Urine cystatin C is a strong predictor for short-term mortality and therapeutic response to Terlipressin in cirrhotic patients with serum creatinine greater than 1.5mg/dl Shin Hee Kim Gangneung Asan Medical Center278 Predictors of response and survival to terlipressin plus albumin or albumin alone for treatment of hepatorenal syndrome-1 (HRS-1): Combined analysis of OT-0401 and REVERSE Thomas D. Porayko Vanderbilt University Medical Center280 Clinical Utilization of Serum Albumin to Ascitic Fluid Albumin Gradient and Ascitic Fluid Protein Concentration in Pediatric Ascites Saachi Nangia Pediatric Gastroenterology281 Multicenter retrospective analysis of the Model for End-stage Liver Disease (MELD) and proton pump inhibitors to predict in the first episode of spontaneous bacterial peritonitis Sakkarin Chirapongsathorn The EMMES Corporation287 The decreased urinary aquaporin2 excretion is a predictive factor for the efficacy of Tolvaptan in patients with hepatic cirrhosis. Perez, Cristiane Villela-Nogueira Rio de Janeiro Federal University290 Goal-Directed Treatment for Portopulmonary Hypertension: Results of a Prospective Trial Sonja Bartolome University of Kansas291 Usefulness of the hepatic venous pressure gradient as a predictor to evaluate the efficacy of tolvaptan in decompensated liver cirrhosis patients with hepatic edema Ai Nakagawa, Masanori Atsukawa, Tomomi Okubo, Taeang Arai, Norio Itokawa, Chisa Kondo, Shunji Fujimori, Katsuhiko Iwakiri Nippon Medical Scool Chiba Hokusoh Hospital292 What is the evolution of Grade 1 ascites in patients with cirrhosis? Lingiah, Phoenix Fung, Maliha Ahmad, Lizza Bojito-Marrero, Nneoma O. Coordinamento Trapianti di fegato, Azienda Ospedaliera Brotzu310 Possible involvement of activating follicular helper T cells in autoimmune hepatitis Naruhiro Kimura, Satoshi Yamagiwa, Hiroki Honda, Toru Setsu, Kentaro Tominaga, Hiroteru Kamimura, Masaaki Takamura, Shuji Terai Niigata university311 Methotrexate therapy for Autoimmune Hepatitis James Haridy Eastern Health312 Features and patterns of concurrent extrahepatic autoimmune diseases in patients with Autoimmune Hepatitis and Overlap/Variant Syndromes: Implications for diagnosis and management Guan Wee Wong, Andrew D. Heneghan Institute of Liver Studies, King's College Hospital, London 313 The Need for Improved Liver Literacy in the US Population Tracy J.

Dolin University of Louisville588 Golgi Stress Response Is Associated with Anti-HIV drug-induced ER Stress and Liver Cell Injury Hui Han, Cheng Ji Univ Southern California589 Acetaldehyde Triggers HCV-Induced Hepatitis Progression: A Proposed Mechanism Murali Ganesan University of Nebraska Medical Center590 Mitochondrial Fission Factor (MFF) is induced and binds to Sab (Sh2BP5) in acetaminophen (APAP) and other JNK dependent hepatotoxicities. Than, Neil Kaplowitz USC KSOM591 Hormesis in cholestatic liver disease; preconditioning with low bile acid concentrations protects against bile acid-toxicity Esther M.

Verhaag, Manon Buist-Homan, Han Moshage, Klaas Nico Faber University of Groningen592 A protective role of C/EBP homologous protein in acetaminophen-induced acute hepatocyte damage in mice Tsutomu Matsubara Osaka City University593 The Effect of Treatment with Chemical Chaperones and Zinc Acetate on Hepatocytes Treated with Excess Copper Shinji Oe, Koichiro Miyagawa, Yuichi Honma, Masaru Harada University of Occupational and Environmental Health, Japan.594 Sumoylation Regulates Lipopolysaccharide-induced Macrophage Activation Modulating Ubiquiting conjugating enzyme 9 Phosphorylation in Mouse Liver and Kupffer Cells Maria Lauda Tomasi Instituto de Investigación Biomédica de Málaga (IBIMA) , Hospital Universitario Virgen de la Victoria, Universidad de Málaga, CIBERehd596 The influence of drug properties and host factors on delayed onset in hepatotoxicity: An analysis of the cohort included in the Spanish DILI Registry.

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